Exosomes from Dendritic Cells Loaded with Chaperone-Rich Cell Lysates Elicit a Potent T Cell Immune Response Against Intracranial Glioma in Mice

B lymphocytes secrete antigen-presenting vesicles.

Graça Raposo, Hans W. Nijman, Willem Stoorvogel et al. · The Journal of Experimental Medicine · 1996 · 3.5K citations · Full text

Life Sciences, Cell Biology, Immunology +11

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

Laurence Zitvogel, Armelle Régnault, Anne Lozier et al. · Nature Medicine · 1998 · 2.2K citations

Medicine, Immunology, Oncology +16

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

Joseph Wolfers, Anne Lozier, Graça Raposo et al. · Nature Medicine · 2001 · 1.6K citations

Life Sciences, Immunology, Oncology +16

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Bernard Escudier, Thierry Dorval, Nathalie Chaput et al. · Journal of Translational Medicine · 2005 · 1.3K citations · Full text

Medicine, Immunology, Oncology +17

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Michael A. Morse, Jennifer Garst, Takuya Osada et al. · Journal of Translational Medicine · 2005 · 1.1K citations · Full text

Life Sciences, Immunology, Oncology +15