Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

Marie Vétizou, Jonathan M. Pitt, Romain Daillère, +35

Science

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

Noëlia Casares, Marie O. Péquignot, Antoine Tesnière, +15

The Journal of Experimental Medicine

ImmunologyImmunoeditingCell DeathImmunotherapyTumor Biology +14

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

Thomas Lener, Mario Gimona, Ludwig Aigner, +53

Journal of Extracellular Vesicles

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

Nathalie Chaput, Patricia Lepage, Clélia Coutzac, +15

Annals of Oncology

InflammationDysbiosisMucosal ImmunologyBaseline Gut MicrobiotaGut Microbiology +12

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Bernard Escudier, Thierry Dorval, Nathalie Chaput, +21

Journal of Translational Medicine

Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1

Stéphane Champiat, Laurent Dercle, Samy Ammari, +8

Clinical Cancer Research

Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non–Small Cell Lung Cancer

Laura Mezquita, Édouard Auclin, Roberto Ferrara, +19

JAMA Oncology

CD4<b>+</b>CD25<b>+</b> regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

François Ghiringhelli, Cédric Menard, Magali Terme, +18

The Journal of Experimental Medicine

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC

Benjamin Besse, Mélinda Charrier, Valérie Lapierre, +25

OncoImmunology

ImmunologyImmunotherapeuticsImmunotherapyFirst Line ChemotherapyTumor Immunology +18

Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells

Fabrice André, Nathalie Chaput, Noël E.C. Schartz, +11

The Journal of Immunology

ImmunologyCurrent Immunization ProtocolsImmunodominanceAntigen ProcessingImmune Cell Therapy +18