Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

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Medicine, Genetics, Molecular Genetics +16

Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

Timo Lotta, Jukka Vidgren, Carola Tilgmann et al. · Biochemistry · 1995 · 1.2K citations

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Creatine Deficiency in the Brain: A New, Treatable Inborn Error of Metabolism

Sylvia Stöckler, U. Holzbach, F. Hanefeld et al. · Pediatric Research · 1994 · 418 citations

Life Sciences, Neurology, Neuroscience +10

Genomic organization of the human catechol <i>O</i>‐methyltransferase gene and its expression from two distinct promoters

Jukka Tenhunen, Marjo Salminen, Kenneth Lundström et al. · European Journal of Biochemistry · 1994 · 331 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility.

Chiun‐Sheng Huang, H D Chern, King‐Jen Chang et al. · PubMed · 1999 · 290 citations

Medicine, Genetics, Oncology +17