Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

Timo Lotta, Jukka Vidgren, Carola Tilgmann, +4

Biochemistry

Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study.

Piero Pollesello, Martti Ovaska, Juha Kaivola, +6

Journal of Biological Chemistry

Levosimendan BindsMolecular PharmacologyCardiac MuscleMolecular PhysiologySignal Transduction +12

Genetic polymorphism of catechol-O-methyltransferase (COMT): correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and Parkinsonian patients in Finland

Ann-Christine Syv nen, Carola Tilgmann, Juha Rhine, +1

Pharmacogenetics

GeneticsComt EnzymeGenetic EpidemiologyHuman PolymorphismGenotype-phenotype Association +17

Binding of Levosimendan, a Calcium Sensitizer, to Cardiac Troponin C

Tia Sorsa, Sami Heikkinen, M.Bret Abbott, +9

Journal of Biological Chemistry

Cardiac MuscleMolecular PhysiologySignal TransductionBiochemistrySecondary Binding Site +11

Distribution of catechol-O-methyltransferase enzyme in rat tissues.

Tuula Karhunen, Carola Tilgmann, Ismo Ulmanen, +2

Journal of Histochemistry & Cytochemistry

Laboratory ImmunologyComt EnzymeGlycobiologyImmunologyPathology +17

Compensatory Mechanisms Associated With the Hyperdynamic Function of Phospholamban-Deficient Mouse Hearts

Guoxiang Chu, Wusheng Luo, Jay P. Slack, +10

Circulation Research

Cardiac MuscleHeart FailurePhospholamban-deficient Mouse HeartsCardiovascular FunctionCellular Physiology +20

Molecular cloning and characterization of rat liver catechol-O-methyltransferase

Marjo Salminen, Kenneth Lundström, Carola Tilgmann, +3

Gene

BiochemistryLiver PhysiologyBiochemical GeneticsHepatotoxicityMolecular Cloning +2

Aspartic proteinase from barley grains is related to mammalian lysosomal cathepsin D

Paula Sarkkinen, Nisse Kalkkinen, Carola Tilgmann, +3

Planta

Barley GrainsCellular EnzymologyBiochemistryNatural SciencesGenetics +6

Expression and Intracellular Localization of Catechol <i>O</i>‐methyltransferase in Transfected Mammalian Cells

Ismo Ulmanen, Johan Peränen, Jukka Tenhunen, +6

European Journal of Biochemistry

Further Evidence for the Cardiac Troponin C Mediated Calcium Sensitization by Levosimendan: Structure-response and Binding Analysis with Analogs of Levosimendan

Jouko Levijoki, Piero Pollesello, Juha Kaivola, +5

Journal of Molecular and Cellular Cardiology

Signal TransductionMolecular PhysiologyBiochemistryMedicinePhysiology +3