Biotechnology and Bioengineering · 1987 · 33 citations · 22 references
EngineeringBiotechnologyChemical EngineeringBiochemical EngineeringFermentation EngineeringReaction EngineeringBiochemical Reaction EngineeringBiofuel ProductionBioprocess KineticsEnzyme KineticsFermentation KineticsKinetic ModelingEnzyme Reaction KineticsImmobilized Cell SystemsInhibition KineticsOptimal Reactor ConfigurationProduct InhibitionProduct Inhibition KineticsSubstrate InhibitionSubstrate Inhibition Kinetics
Kinetic expressions for the fermentative production of relatively high concentrations [12% (w/v)] of ethanol have been examined. Several expressions which account for both substrate and product inhibition have been formulated, and have been applied to suspended cell and immobilized cell reactors. Experimental data have been used to validate the kinetic expressions used, and the impact of combined inhibition on optimal reactor configuration has been assessed. The process implications of combined substrate and product inhibition for suspended and immobilized cell systems have been discussed.
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