Inhibition of Both Thioredoxin Reductase and Glutathione Reductase may Contribute to the Anticancer Mechanism of TH-302

[59] Glutathione reductase

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A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.

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Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

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Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

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Substitution of the Thioredoxin System for Glutathione Reductase in <i>Drosophila melanogaster</i>

Stefan M. Kanzok, A. Fechner, Holger Bauer et al. · Science · 2001 · 400 citations

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