Holger Bauer

Substitution of the Thioredoxin System for Glutathione Reductase in <i>Drosophila melanogaster</i>

Stefan M. Kanzok, A. Fechner, Holger Bauer et al. · Science · 2001 · 400 citations

Life Sciences, Biochemistry, Entomology +17

Active sites of thioredoxin reductases: Why selenoproteins?

Stephan Gromer, Linda Johansson, Holger Bauer et al. · Proceedings of the National Academy of Sciences · 2003 · 224 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

5-Substituted Tetrazoles as Bioisosteres of Carboxylic Acids. Bioisosterism and Mechanistic Studies on Glutathione Reductase Inhibitors as Antimalarials

Christophe Biot, Holger Bauer, R. Heiner Schirmer et al. · Journal of Medicinal Chemistry · 2004 · 179 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Glutathione Reductase-Catalyzed Cascade of Redox Reactions To Bioactivate Potent Antimalarial 1,4-Naphthoquinones – A New Strategy to Combat Malarial Parasites

Tobias Müller, Laure Johann, Beate Jannack et al. · Journal of the American Chemical Society · 2011 · 117 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A Fluoro Analogue of the Menadione Derivative 6-[2‘-(3‘-Methyl)-1‘,4‘-naphthoquinolyl]hexanoic Acid Is a Suicide Substrate of Glutathione Reductase. Crystal Structure of the Alkylated Human Enzyme

Holger Bauer, Karin Fritz‐Wolf, Andreas Winzer et al. · Journal of the American Chemical Society · 2006 · 91 citations

Life Sciences, Biochemistry, Pharmacology +16