Maximum production in a bakers' yeast fed‐batch culture by a tubing method

Abstract

Abstract A feedback control system of the glucose feed rate in a bakers' yeast fed‐batch culture was developed by keeping the ethanol concentration constant. A PID controller and on–off controller were applied and discussed with the aid of the porous Teflon tubing method. Experimental results showed the effectiveness of the control system for avoiding the glucose effect and glucose starvation. It was shown that the feedback control system developed hare could achieve a maximum specific growth rate of 0.3 h −1 or a maximum cell yield of 0.5 g cell/g glucose in the fedhyphen;batch culture.