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Exploring the isoform selectivity of TGX-221 related pyrido[1,2-a]pyrimidinone-based Class IA PI 3-kinase inhibitors: Synthesis, biological evaluation and molecular modelling

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignPharmacotherapyBiological EvaluationDrug DevelopmentChemical BiologyPharmacologyIsoform SelectivityDrug Discovery