Peter R. Shepherd

The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins

Laura Harrington, Greg M. Findlay, Simon Wigfield et al. · The Journal of Cell Biology · 2004 · 1.1K citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

Khanh Bao Tran, Justin J. Lang, Kelly Compton et al. · The Lancet · 2022 · 936 citations · Full text

Medicine, Oncology, Preventive Medicine +17

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

B. Nave, D. Margriet Ouwens, Dominic J. Withers et al. · Biochemical Journal · 1999 · 923 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

PI 3-kinase p110β: a new target for antithrombotic therapy

Shaun P. Jackson, Simone M. Schoenwaelder, Isaac Goncalves et al. · Nature Medicine · 2005 · 589 citations

Medicine, Molecular Medicine, Pharmacology +15

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue.

Peter R. Shepherd, Luigi Gnudi, Effie Tozzo et al. · Journal of Biological Chemistry · 1993 · 523 citations · Full text

Life Sciences, Endocrinology, Physiology +17