Combretastatin CA-4 and combretastatin derivative induce mitotic catastrophe dependent on spindle checkpoint and caspase-3 activation in non-small cell lung cancer cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

Xuesong Liu, Hua Zou, Clive A. Slaughter et al. · Cell · 1997 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

Hideki Sakahira, Masato Enari, Shigekazu Nagata · Nature · 1998 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +12

A New Method for the Cytofluorometric Analysis of Mitochondrial Membrane Potential Using the J-Aggregate Forming Lipophilic Cation 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine Iodide (JC-1)

Andrea Cossarizza, M. Baccarani-Contri, Galina Kalashnikova et al. · Biochemical and Biophysical Research Communications · 1993 · 1K citations · Full text

Life Sciences, Biophysics, Cell Biology +10

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

M A Jordan, K Wendell, Sheila M. Gardiner et al. · PubMed · 1996 · 783 citations

Life Sciences, Cancer Biology, Cell Biology +17