Novel applications of resin bound α-amino acids for the synthesis of benzodiazepines (via Wang resin) and ketopiperazines (via hydroxymethyl resin)

The α‐Addition of Immonium Ions and Anions to Isonitriles Accompanied by Secondary Reactions

Ivar Ugi · Angewandte Chemie International Edition in English · 1962 · 593 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +11

Multicomponent reactions in organic chemistry

Ivar Ugi, Alexander Dömlingꝉ, Werner Hörl · Endeavour · 1994 · 593 citations

Natural Sciences, Chemistry, Organic Chemistry +13

A New Heterocyclic Multicomponent Reaction For the Combinatorial Synthesis of Fused 3-Aminoimidazoles

Hugues Bienaymé, Kamel Bouzid · Angewandte Chemie International Edition · 1998 · 426 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation

Christopher Blackburn, Bing Guan, Paul Fleming et al. · Tetrahedron Letters · 1998 · 371 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Postcondensation Modifications of Ugi Four-Component Condensation Products:  1-Isocyanocyclohexene as a Convertible Isocyanide. Mechanism of Conversion, Synthesis of Diverse Structures, and Demonstration of Resin Capture

Thomas A. Keating, Robert W. Armstrong · Journal of the American Chemical Society · 1996 · 288 citations

Natural Sciences, Biochemistry, Chemistry +12