Richard Labaudinière

Tafamidis for transthyretin familial amyloid polyneuropathy

Teresa Coelho, Luı́s F. Maia, Ana Silva et al. · Neurology · 2012 · 774 citations · Full text

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

Christine Bulawa, Stephen Connelly, Michael J. DeVit et al. · Proceedings of the National Academy of Sciences · 2012 · 728 citations · Full text

New 4-Point Pharmacophore Method for Molecular Similarity and Diversity Applications:  Overview of the Method and Applications, Including a Novel Approach to the Design of Combinatorial Libraries Containing Privileged Substructures

Jonathan Mason, Isabelle Morize, Paul R. Menard et al. · Journal of Medicinal Chemistry · 1999 · 376 citations · Full text

Drug Target, Novel Approach, Molecular Biology +19

Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy

Teresa Coelho, Luı́s F. Maia, Ana Silva et al. · Journal of Neurology · 2013 · 333 citations · Full text

Alzheimer's Disease, Long-term Effects, Disease Progression +10

The Discovery of Tadalafil:  A Novel and Highly Selective PDE5 Inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1‘,2‘:1,6]pyrido[3,4-<i>b</i>]indole-1,4-dione Analogues

Alain Daugan, Pascal Grondin, Cécile Ruault et al. · Journal of Medicinal Chemistry · 2003 · 279 citations · Full text

Combinatorial Chemistry, Molecular Pharmacology, Medicinal Chemistry +14