Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.3K citations · Full text

Genome Instability, Novel Gene, Genetic Disorder +10

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

Fiona Doetsch, Isabelle Caillé, Daniel A. Lim et al. · Cell · 1999 · 3.9K citations · Full text

Neuroregeneration, Ependyma, Neurophysiology +14

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Developmental Biology +9

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

Genetic Diseases, Genome Instability, Novel Gene +10

Neuronal replacement from endogenous precursors in the adult brain after stroke

Andreas Arvidsson, Tove Collin, Deniz Kirik et al. · Nature Medicine · 2002 · 2.8K citations · Full text

Endogenous Precursors, Brain Circulation, Social Sciences +17