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Discovery of novel and orally active NR2B-selective N-methyl-d-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity

Pyridinol DerivativesBiochemistryFunctional SelectivityMedicineNatural SciencesMechanism Of ActionPharmacological AgentNeuropharmacologyPharmacotherapyDrug DevelopmentChemical BiologyPharmacologyActive Nr2b-selective N-methyl-d-aspartateDrug Discovery