Isao Sakurada

Discovery and Preclinical Characterization of 1-Methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1 <i>H</i> -pyrazolo-[3,4- <i>b</i> ]pyrazine (PF470): A Highly Potent, Selective, and Efficacious Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator

Lei Zhang, Gayatri Balan, Gabriela Barreiro et al. · Journal of Medicinal Chemistry · 2014 · 51 citations · Full text

Direct Chlorohydrin and Acetoxy Alcohol Synthesis from Olefins Promoted by a Lewis Acid, Bis(trimethylsilyl) Peroxide and (CH₃)₃SiX

Isao Sakurada, Shingo Yamasaki, Richard Göttlich et al. · Journal of the American Chemical Society · 2000 · 41 citations

Olefins Promoted, Medicinal Chemistry, Engineering +13

Dichlorotin oxide-catalyzed new direct functionalization of olefins: synthesis of trans β-azidohydrins and 1,2-diols

Isao Sakurada, Shingo Yamasaki, Motomu Kanai et al. · Tetrahedron Letters · 2000 · 18 citations

Combinatorial Chemistry, Engineering, Trans β-Azidohydrins +7

Development of a novel tricyclic class of potent and selective FIXa inhibitors

Dong‐Fang Meng, Patrick André, Thomas J. Bateman et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 16 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +10

Development of a novel class of potent and selective FIXa inhibitors

Ting Zhang, Patrick André, Thomas J. Bateman et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 16 citations · Full text

Medicinal Chemistry, Novel Therapy, Biochemistry +11