Concepedia

Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium

Yan Zhao, Qiang Li, Wenjun Zhao, Jia Li, Yan Sun, Kang Liu, Baolin Liu, Ning Zhang

Journal of Ethnopharmacology · 2015 · 108 citations · 32 references

DOI

Concepts

References

32

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

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Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

Jeffery S. Cox, Caroline E. Shamu, Peter Walter · Cell · 1993 · 1.2K citations

, , +8

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

Suneng Fu, Ling Yang, Ping Li et al. · Nature · 2011 · 1K citations

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IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, Paurush Praveen et al. · Cell Metabolism · 2012 · 832 citations · Full text

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