Concepedia

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

Suneng Fu, Ling Yang, Ping Li, Oliver Hofmann, Lee H. Dicker, Xihong Lin, Steven M. Watkins, Alexander R. Ivanov, Gökhan S. Hotamışlıgil

Nature · 2011 · 1K citations · 21 references

DOI

Concepts

References

21

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Umut Özcan, Erkan Yılmaz, Lale Özcan et al. · Science · 2006 · 2.4K citations · Full text

, , +17

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

Haiming Cao, Kristin A. Gerhold, Jared R. Mayers et al. · Cell · 2008 · 1.1K citations · Full text

, , +14

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

Hélène L. Kammoun, Hervé Chabanon, Isabelle Hainault et al. · Journal of Clinical Investigation · 2009 · 739 citations · Full text

, , +17

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

Gang Li, Marco Mongillo, King‐Tung Chin et al. · The Journal of Cell Biology · 2009 · 583 citations · Full text

, , +16

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

Nica M. Borradaile, Xianlin Han, Jeffrey D. Harp et al. · Journal of Lipid Research · 2006 · 566 citations · Full text

, , +17