Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

Ling Yang, Ping Li, Suneng Fu, +2

Cell Metabolism

ObesityMetabolic SyndromeCell AutophagyHepatologyDefective Hepatic Autophagy +11

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

Suneng Fu, Ling Yang, Ping Li, +6

Nature

ObesityMetabolic SyndromeEnergy HomeostasisHepatologyLiver Physiology +10

Zcchc11-dependent uridylation of microRNA directs cytokine expression

Matthew R. Jones, Lee J. Quinton, Matthew T. Blahna, +5

Nature Cell Biology

ImmunologyMicrorna DetectionSmall RnaGene ExpressionMedicine +4

S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

Ling Yang, Ediz S. Calay, Jason Fan, +6

Science

Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity

Suneng Fu, Abdullah Yalçın, Grace Y. Lee, +6

Science Translational Medicine

<i>empty pericarp2</i> Encodes a Negative Regulator of the Heat Shock Response and Is Required for Maize Embryogenesis

Suneng Fu, Robert Meeley, Michael J. Scanlon

The Plant Cell

Negative RegulatorGeneticsMolecular GeneticsEmp2 GeneMaize Kernels +16

Amino acid is a major carbon source for hepatic lipogenesis

Yilie Liao, Qishan Chen, Lei Liu, +11

Cell Metabolism

NutritionAmino AcidsFatty Liver DiseaseOxidative StressObesity +18

Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance

Lei Liu, Tian Li, Yilie Liao, +8

Cell Metabolism

Metabolic SyndromeNutritionBiochemistryTriose Kinase ControlsLipogenic Potential +10

Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting

Suneng Fu, Jason Fan, Joshua Blanco, +4

PLoS Genetics

Metabolic RemodelingFatty Liver DiseaseInsulin SignalingProtein SynthesisObesity +18

The maize heat shock factor-binding protein paralogs EMP2 and HSBP2 interact non-redundantly with specific heat shock factors

Suneng Fu, Peter Rogowsky, Lutz Nover, +1

Planta

Protein FunctionProtein ExpressionGeneticsMolecular BiologyProtein Genetics