Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

Life Sciences, Molecular Biology, Molecular Genetics +7

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +11

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

John R. Riordan, Kathryn L. Deuchars, Norbert Kartner et al. · Nature · 1985 · 841 citations

Medicine, Molecular Biology, Oncology +7

Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells

Alex M. Chen, Min Zhang, Dongguang Wei et al. · Small · 2009 · 660 citations · Full text

Pharmacy, Oncology, Pharmaceutics +17

Co-delivery of drugs and DNA from cationic core–shell nanoparticles self-assembled from a biodegradable copolymer

Yong Wang, Shujun Gao, Wenhui Ye et al. · Nature Materials · 2006 · 655 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14