Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells

Abstract

Co-delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug-resistance cancer cells with minimal premature release significantly enhances the efficacy of chemotherapy by conquering the nonpump resistance and possibly bypassing the efflux pump resistance (see image). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.