Small · 2007 · 1K citations · 24 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanomaterialsNanoparticle Drug DeliveryDrug EncapsulationInorganic NanoparticlesNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle FormulationsCancer NanotherapyDrug Delivery NanocarriersSilica-based Nanoparticles
Special delivery: The hydrophobic anticancer drug camptothecin was incorporated into fluorescent mesoporous silica nanoparticles (see image) and delivered to various cancer cells to induce cell death. These results suggest a method to overcome the insolubility problem of many anticancer drugs, which is considered to be one of the major challenges in cancer therapy.
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Ordered mesoporous molecular sieves synthesized by a liquid-crystal template mechanism
Charles T. Kresge, M. E. Leonowicz, Wiesław J. Roth et al. · Nature · 1992 · 16.1K citations
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The emerging nanomedicine landscape
Volker Wagner, Anwyn Dullaart, Annekatrin Bock et al. · Nature Biotechnology · 2006 · 1.6K citations