Mesoporous Silica Nanoparticles as a Delivery System for Hydrophobic Anticancer Drugs

Jie Lü, Monty Liong, Jeffrey I. Zink, Fuyuhiko Tamanoi

Small · 2007 · 1K citations · 24 references

Concepts

Abstract

Special delivery: The hydrophobic anticancer drug camptothecin was incorporated into fluorescent mesoporous silica nanoparticles (see image) and delivered to various cancer cells to induce cell death. These results suggest a method to overcome the insolubility problem of many anticancer drugs, which is considered to be one of the major challenges in cancer therapy.

References

24