Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells

A simple technique for quantitation of low levels of DNA damage in individual cells

Narendra P. Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research · 1988 · 10.8K citations · Full text

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

Life Sciences, Cell Biology, Molecular Biology +12

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Scott W. Lowe, H. Earl Ruley, Tyler Jacks et al. · Cell · 1993 · 2.9K citations

Life Sciences, Cancer Biology, Oncology +14

Thymocyte apoptosis induced by p53-dependent and independent pathways

Alan R. Clarke, Colin A. Purdie, David J. Harrison et al. · Nature · 1993 · 2.3K citations

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

Laura R. Livingstone, Alicia White, Jason Sprouse et al. · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +16