Concepedia

Coexpression of Human cdk5 and Its Activator p35 with Human Protein Tau in Neurons in Brain of Triple Transgenic Mice

Chris Van den Haute, Kurt Spittaels, Jo Van Dorpe, Reena Lasrado, Kris Vandezande, Isabelle Laenen, Hugo Geerts, F. Van Leuven

Neurobiology of Disease · 2001 · 81 citations · 54 references

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54

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Michel Goedert, Maria Grazia Spillantini, Ross Jakes et al. · Neuron · 1989 · 2.5K citations

, , +16

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolić et al. · Nature · 1999 · 1.5K citations

, , +10

Neurotoxicity induces cleavage of p35 to p25 by calpain

Ming‐Sum Lee, Young T. Kwon, Mingwei Li et al. · Nature · 2000 · 1.1K citations

, , +9

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Li‐Huei Tsai, Ivana Delalle, Verne S. Caviness et al. · Nature · 1994 · 923 citations

, , +7

A family of human cdc2‐related protein kinases.

Matthew Meyerson, G H Enders, Chia‐Ling Wu et al. · The EMBO Journal · 1992 · 921 citations · Full text

, , +8