Concepedia

γ-Glutamyl cysteine and γ-glutamyl valine inhibit TNF-α signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor

Hua Zhang, Jennifer Kovacs-Nolan, Tomohiro Kodera, Yuzuru Eto, Yoshinori Mine

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2015 · 180 citations · 36 references

DOI

Concepts

References

36

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

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A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

Isao Okayasu, Shigeru Hatakeyama, Masahiro Yamada et al. · Gastroenterology · 1990 · 2.4K citations

, , +16

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

Da Young Oh, Saswata Talukdar, Eun Ju Bae et al. · Cell · 2010 · 2.4K citations · Full text

, , +12

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

Joseph A. DiDonato, Makio Hayakawa, David M. Rothwarf et al. · Nature · 1997 · 2.1K citations

, , +14

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

, , +5