Prognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.

Mitsushige Nakao, S Yokota, Toshiki Iwai et al. · PubMed · 1996 · 1.2K citations

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

Yukiya Yamamoto · Blood · 2001 · 1.1K citations

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

Andrei V. Krivtsov, Zhaohui Feng, Madeleine E. Lemieux et al. · Cancer Cell · 2008 · 547 citations · Full text

Chromatin, Epigenetic Change, Dna Methylation +6

Inhibition of FLT3 in MLL

Scott A. Armstrong, Andrew L. Kung, Meghann E. Mabon et al. · Cancer Cell · 2003 · 398 citations · Full text

Molecular Pharmacology, Molecular Regulation, Medicine +5

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

Matthew G. Guenther, Lee N. Lawton, Tatiana Rozovskaia et al. · Genes & Development · 2008 · 277 citations · Full text

Epigenetic Change, Genetics, Mixed-phenotype Acute Leukemia +20