Concepedia

Benzo[a]pyrene induces complex H2AX phosphorylation patterns by multiple kinases including ATM, ATR, and DNA-PK

Chunlan Yan, Jing Lü, Guanglin Zhang, Tieer Gan, Qunli Zeng, Zhengping Shao, Penelope J. Duerksen-Hughes, Jun Yang

Toxicology in Vitro · 2010 · 33 citations · 30 references

DOI

Concepts

References

30

ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks

Sandeep Burma, Benjamin P. Chen, Michael Murphy et al. · Journal of Biological Chemistry · 2001 · 1.9K citations · Full text

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Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

Linda J Kuo, Li‐Xi Yang · PubMed · 2008 · 1.2K citations

, , +17

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

Jann N. Sarkaria, Ericka C. Busby, Randal S. Tibbetts et al. · PubMed · 1999 · 1K citations

, , +16

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

Irene M. Ward, Kay Minn, Katherine G. Jorda et al. · Journal of Biological Chemistry · 2003 · 358 citations · Full text

, , +17

Caffeine inhibits the checkpoint kinase ATM

Alessandra Blasina, Brendan D. Price, Gaetan A. Turenne et al. · Current Biology · 1999 · 292 citations · Full text

, , +9