RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly

Michael S.Y. Huen, Robert A. Grant, Isaac A. Manke, +4

Cell

ChromatinGenome InstabilityChromatin RemodelingMedicineDna-damage Signal +6

p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice

Irene M. Ward, Kay Minn, Jan van Deursen, +1

Molecular and Cellular Biology

Tumor BiologyGenome InstabilityChromatinMedicineTumor Suppression +11

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

Irene M. Ward, Kay Minn, Katherine G. Jorda, +1

Journal of Biological Chemistry

The genomic landscape of small intestine neuroendocrine tumors

Michaela S. Banck, Rahul Kanwar, Amit Kulkarni, +15

Journal of Clinical Investigation

EngineeringPathologyCancer BiologyTumor BiologyEndocrine Oncology +14

53BP1 is required for class switch recombination

Irene M. Ward, Bernardo Reina‐San‐Martin, Alexandru Olaru, +9

The Journal of Cell Biology

UV-induced Ataxia-telangiectasia-mutated and Rad3-related (ATR) Activation Requires Replication Stress

Irene M. Ward, Kay Minn, Junjie Chen

Journal of Biological Chemistry

Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples

Stefan Graw, Richard Meier, Kay Minn, +6

Scientific Reports

53BP1 Cooperates with p53 and Functions as a Haploinsufficient Tumor Suppressor in Mice

Irene M. Ward, Simone Difilippantonio, Kay Minn, +7

Molecular and Cellular Biology

ImmunologyHistone H2axCancer BiologyTumor BiologyProtein 1 +14

The Tandem BRCT Domain of 53BP1 Is Not Required for Its Repair Function

Irene M. Ward, Ja‐Eun Kim, Kay Minn, +3

Journal of Biological Chemistry

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

Xuan Zhang, Lihua Cheng, Kay Minn, +4

Oncotarget