5-Ethynyl-2(1H)-pyrimidinone: Aldehyde oxidase-activation to 5-ethynyluracil, a mechanism-based inactivator of dihydropyrimidine dehydrogenase

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

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Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion.

Barry Harris, Seng-Jaw Soong, Robert B. Diasio · PubMed · 1990 · 445 citations

Medicine, Pharmacokinetics, Pharmacology +17

A comparison of the specificities of xanthine oxidase and aldehyde oxidase

Thomas A. Krenitsky, Shannon M. Neil, Gertrude B. Elion et al. · Archives of Biochemistry and Biophysics · 1972 · 342 citations

Life Sciences, Biochemistry, Biocatalysis +3

Hepatic Aldehyde Oxidase

K.V. Rajagopalan, Irwin Fridovich, Philip Handler · Journal of Biological Chemistry · 1962 · 284 citations · Full text