Joan A. Harrington

5-ethynyluracil (776C85): Inactivation of dihydropyrimidine dehydrogenase in vivo

Thomas Spector, Joan A. Harrington, David Porter · Biochemical Pharmacology · 1993 · 96 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +4

2-Acetylpyridine thiocarbonohydrazones. Potent inactivators of herpes simplex virus ribonucleotide reductase

Todd A. Blumenkopf, Joan A. Harrington, Cecilia S. Koble et al. · Journal of Medicinal Chemistry · 1992 · 62 citations

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.

T Spector, Joan A. Harrington, R.W. Morrison et al. · Proceedings of the National Academy of Sciences · 1989 · 60 citations · Full text

Viral Replication, Dgtp Pool, Acyclovir Triphosphate-to-dgtp Ratio +21

Attenuation of the antitumor activity of 5-fluorouracil by (R)-5-fluoro-5,6-dihydrouracil.

T Spector, S Cao, Y M Rustum et al. · PubMed · 1995 · 59 citations

Molecular Pharmacology, Medicinal Chemistry, Tumor Biology +14

Significance of Individual Point Mutations, T202C and C314T, in the Human Lewis (FUT3) Gene for Expression of Lewis Antigens by the Human α(1,3/1,4)-Fucosyltransferase, Fuc-TIII

Anders Elmgren, Rosella Mollicone, Marieta Costache et al. · Journal of Biological Chemistry · 1997 · 54 citations · Full text

Histocompatibility, Human α, Genetics +18