Concepedia

Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer

Daniel Shiu‐Hin Chan, Hui Yang, Maria Hiu‐Tung Kwan, Zhen Cheng, Paul Lee, Li‐Ping Bai, Zhi‐Hong Jiang, Chun‐Yuen Wong, Wang-Fun Fong, Chung‐Hang Leung,

Biochimie · 2011 · 96 citations · 42 references

DOI

Concepts

References

42

Molecular cloning: A laboratory manual

Prescott L. Deininger · Analytical Biochemistry · 1990 · 86.2K citations

, , +11

The price of innovation: new estimates of drug development costs

Joseph A. DiMasi, Ronald W. Hansen, Henry G. Grabowski · Journal of Health Economics · 2003 · 4.3K citations · Full text

, , +14

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- <i>MYC</i> transcription

Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss et al. · Proceedings of the National Academy of Sciences · 2002 · 2.2K citations

, , +17

Crystal structure of parallel quadruplexes from human telomeric DNA

Gary N. Parkinson, Michael P. H. Lee, Stephen Neidle · Nature · 2002 · 2K citations

, , +12

G-quadruplexes in promoters throughout the human genome

J Huppert, Shankar Balasubramanian · Nucleic Acids Research · 2006 · 1.3K citations · Full text

, , +12