Characterization of Long-Circulating Cationic Nanoparticle Formulations Consisting of a Two-Stage PEGylation Step for the Delivery of siRNA in a Breast Cancer Tumor Model

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Direct Gene Transfer into Mouse Muscle in Vivo

Jon A. Wolff, Robert W. Malone, Phillip Williams et al. · Science · 1990 · 4.2K citations

Life Sciences, Genetics, Molecular Biology +16

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

Michael J. Hope, Marcel B. Bally, G. A. Webb et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 2.1K citations

Life Sciences, Biochemistry, Biophysics +13

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Jennifer A. Lockridge, Lucinda Shaw, Karin S. Blanchard et al. · Nature Biotechnology · 2005 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +12