Concepedia

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Jennifer A. Lockridge, Lucinda Shaw, Karin S. Blanchard, Kristi Jensen, Wendy Breen, Kimberly Hartsough, Lynn Machemer, Susan F. Radka, Vasant Jadhav, Narendra K. Vaish,

Nature Biotechnology · 2005 · 1.2K citations · 17 references

DOI

Concepts

References

17

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

F Liu, Young Song, D Liu · Gene Therapy · 1999 · 1.7K citations

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Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

Adam D. Judge, Vandana Sood, Janet R. Shaw et al. · Nature Biotechnology · 2005 · 1.3K citations

, , +16

Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

Veit Hornung, Margit Guenthner‐Biller, Carole Bourquin et al. · Nature Medicine · 2005 · 1.2K citations · Full text

, , +14

siRNA function in RNAi: A chemical modification analysis

Ya‐Lin Chiu, Tariq M. Rana · RNA · 2003 · 856 citations · Full text

, , +17

In vivo activity of nuclease-resistant siRNAs

Juliana M. Layzer, Anton P. McCaffrey, Alice Tanner et al. · RNA · 2004 · 571 citations · Full text

, , +15