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2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles

Medicinal ChemistryMedicineDrug DiscoveryRational Drug DesignPharmacological AgentPharmacotherapyDrug DevelopmentSelective Akt InhibitorsPharmacologyPharmaceutical Chemistry2,3,5-Trisubstituted PyridinesBiomolecular EngineeringPart Ii