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(2,6-dimethylphenylsulphonyl)nitromethane: A new structural type of aldose reductase inhibitor which follows biphasic kinetics and uses an allosteric binding site

Medicinal ChemistryAldo-keto ReductaseAldehyde DehydrogenaseBiochemistryBiphasic KineticsNatural SciencesMedicineAllosteric Binding SiteStructure-function Enzyme KineticsAldose Reductase InhibitorChemical BiologyPharmacologyDrug Discovery