Induction and activation of antiviral enzyme 2′,5′-oligoadenylate synthetase by in vitro transcribed insulin mRNA and other cellular RNAs

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mRNA Is an Endogenous Ligand for Toll-like Receptor 3

Katalin Karikó, Houping Ni, John Capodici et al. · Journal of Biological Chemistry · 2004 · 1K citations · Full text

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The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes

Alberto Pugliese, Markus Zeller, Alarico Fernandez et al. · Nature Genetics · 1997 · 947 citations

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pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

Ian M. Kerr, R.E. Brown · Proceedings of the National Academy of Sciences · 1978 · 791 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

S. T. Bennett, Anneke Lucassen, Stephen Gough et al. · Nature Genetics · 1995 · 754 citations

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