Concepedia

The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes

Alberto Pugliese, Markus Zeller, Alarico Fernandez, Laura J. Zalcberg, Richard J. Bartlett, Camillo Ricordi, Massimo Pietropaolo, George S. Eisenbarth, Simon T. Bennett, Dhavalkumar D. Patel

Nature Genetics · 1997 · 947 citations · 30 references

DOI

Concepts

References

30

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus

Petros Vafiadis, Simon T. Bennett, John A. Todd et al. · Nature Genetics · 1997 · 816 citations

, , +13

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

S. T. Bennett, Anneke Lucassen, Stephen Gough et al. · Nature Genetics · 1995 · 754 citations

, , +10

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

Graeme I. Bell, Shiro Horita, John H. Karam · Diabetes · 1984 · 744 citations

, , +10

The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences

Graeme I. Bell, Mark Selby, William J. Rutter · Nature · 1982 · 524 citations

, , +12

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide

Eric Sebzda, Valerie A. Wallace, John P. Mayer et al. · Science · 1994 · 489 citations

, , +16