Expedient approach for the synthesis of novel indenothiophene derivatives

Use of isogenic human cancer cells for high-throughput screening and drug discovery

C Torrance, Vijai Agrawal, Bert Vogelstein et al. · Nature Biotechnology · 2001 · 234 citations

Medicine, Cell Biology, Oncology +12

Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor

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Pharmacy, Medicinal Chemistry, Pharmacology +10

Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells

Lee D. Jennings, Scott L. Kincaid, Yanong D. Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 75 citations

Medicine, Oncology, Pharmacology +11

Evolution of the Thienopyridine Class of Inhibitors of IκB Kinase-β:  Part I:  Hit-to-Lead Strategies

Tina M. Morwick, Angela Berry, Janice R. Brickwood et al. · Journal of Medicinal Chemistry · 2006 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Studies on dihydropyridines. III. Synthesis of 4,7-dihydrothieno(2,3-b)pyridines with vasodilator and antihypertensive activities.

Ikuo Adachi, Teruo Yamamori, Yoshiharu Hiramatsu et al. · Chemical and Pharmaceutical Bulletin · 1988 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17