Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

Michaël Weber, Jonathan Davies, David Wittig et al. · Nature Genetics · 2005 · 1.8K citations

Medicine, Genetics, Molecular Genetics +16

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

Navneet K. Dhillon, Bharat B. Aggarwal, Robert A. Newman et al. · Clinical Cancer Research · 2008 · 1.3K citations

Medicine, Oncology, Pharmacology +15

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Curcumin, a Novel p300/CREB-binding Protein-specific Inhibitor of Acetyltransferase, Represses the Acetylation of Histone/Nonhistone Proteins and Histone Acetyltransferase-dependent Chromatin Transcription

Karanam Balasubramanyam, Radhika A. Varier, Mohammad Altaf et al. · Journal of Biological Chemistry · 2004 · 819 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

Epigenetic Reactivation of Tumor Suppressor Genes by a Novel Small-Molecule Inhibitor of Human DNA Methyltransferases

Bodo Brueckner, Regine García Boy, Paweł Siedlecki et al. · Cancer Research · 2005 · 542 citations

Medicine, Molecular Biology, Oncology +16