Concepedia

Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series

Oluyinka M. Green, Andrew R. McKenzie, Adam B. Shapiro, Ludovic R. Otterbein, Haihong Ni, Arthur D. Patten, S. Stokes, Robert Albert, Sameer Kawatkar, J. Breed

Bioorganic & Medicinal Chemistry Letters · 2012 · 26 citations · 8 references

DOIFull text

Open access

Concepts

References

8

Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis

Dominique Mengin‐Lecreulx, Jean van Heijenoort · Journal of Bacteriology · 1994 · 203 citations · Full text

, , +17

Biosynthesis of lipid A precursors in Escherichia coli. A cytoplasmic acyltransferase that converts UDP-N-acetylglucosamine to UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.

Matt S. Anderson, C R Raetz · Journal of Biological Chemistry · 1987 · 185 citations · Full text

, , +16

Crystal structure of the bifunctional N‐acetylglucosamine 1‐phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily

K. Brown · The EMBO Journal · 1999 · 184 citations

, , +10

Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli

Dominique Mengin‐Lecreulx, Jean van Heijenoort · Journal of Bacteriology · 1993 · 165 citations · Full text

, , +14

The Eukaryotic UDP-N-Acetylglucosamine Pyrophosphorylases

Toshiyuki Mio, Tomio Yabe, Mikio Arisawa et al. · Journal of Biological Chemistry · 1998 · 161 citations · Full text

, , +13