The Plasminogen Activator/Plasmin System Is Essential for Development of the Joint Inflammatory Phase of Collagen Type II-Induced Arthritis

Autoimmunity to type II collagen an experimental model of arthritis.

David E. Trentham, Alexander S. Townes, A H Kang · The Journal of Experimental Medicine · 1977 · 1.6K citations · Full text

Immunology, Type Ii Collagen, Pathology +17

Physiological consequences of loss of plasminogen activator gene function in mice

Peter Carmeliet, Luc Schoonjans, L Kieckens et al. · Nature · 1994 · 1.1K citations

Knockout Mouse, Induced Pluripotent Stem Cell, Signal Transduction +10

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

Zena Werb, Carlo L. Mainardi, Carol A. Vater et al. · New England Journal of Medicine · 1977 · 687 citations

Impaired wound healing in mice with a disrupted plasminogen gene

John Rømer, Thomas H. Bugge, Charles Fyke et al. · Nature Medicine · 1996 · 563 citations

Inflammation, Immunology, Wound Care +9

Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes

James Edwards, Geraldine Cambridge · Lara D. Veeken · 2001 · 517 citations · Full text

Clinical Immunology, Immunology, Immune Regulation +17