Two relatively distinct patterns of ameloblastoma: an anti‐apoptotic proliferating site in the outer layer (periphery) and a pro‐apoptotic differentiating site in the inner layer (centre)

Abstract

Ameloblastoma has much more apoptosis-inhibiting protein than the apoptosis-modulating protein. Ameloblastoma has two relatively distinct patterns, an anti-apoptotic proliferating site in the outer layer (periphery) and a pro-apoptotic differentiating site in the inner layer (centre). The acanthomatous area, which was stained strongly by bak antibody and contained numerous terminally apoptotic cells, was considered as the differentiated area.