Antioxidants successfully reduce ROS production in propionic acidemia fibroblasts

The metabolic and molecular bases of inherited disease

Ying-Tsong Chen · Medical Entomology and Zoology · 2001 · 6.9K citations

Disease Mechanism, Genetic Disorder, Genetics +6

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

Nathan L. Price, Ana P. Gomes, Alvin J. Y. Ling et al. · Cell Metabolism · 2012 · 1.5K citations · Full text

Reductive Stress, Biochemistry, Mitochondrial Function +8

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

Geoffrey F. Kelso, Carolyn M. Porteous, Carolyn V. Coulter et al. · Journal of Biological Chemistry · 2001 · 1.1K citations · Full text

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

Meagan J. McManus, Michael P. Murphy, James L. Franklin · Journal of Neuroscience · 2011 · 421 citations · Full text

Spatial Memory Retention, Mitochondrial Dysfunction, Cell Death +19

Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4).

Gerrit Spanier, Huiyan Xu, Ning Xia et al. · PubMed · 2009 · 288 citations

Nadph Oxidase, Lipid Peroxidation, Redox Biology +18