Detection and Characterization of Aggregates, Prefibrillar Amyloidogenic Oligomers, and Protofibrils Using Fluorescence Spectroscopy

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

Thioflavine T interaction with synthetic Alzheimer's disease <i>β</i>‐amyloid peptides: Detection of amyloid aggregation in solution

Harry LeVine · Protein Science · 1993 · 2.2K citations · Full text

Study of the “molten globule” intermediate state in protein folding by a hydrophobic fluorescent probe

Gennady V. Semisotnov, O.I. Razgulyaev, Vladimir N. Uversky et al. · Biopolymers · 1991 · 1.3K citations

Protein Chemistry, Hydrophobic Fluorescent Probe, Protein Assembly +13

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T

Hironobu Naiki, Keiichi Higuchi, Masanori Hosokawa et al. · Analytical Biochemistry · 1989 · 1.2K citations

Fluorometric Determination, Alzheimer's Disease, Engineering +10

Fibril in senile systemic amyloidosis is derived from normal transthyretin.

Per Westermark, Knut Sletten, Gibbons G. Cornwell · Proceedings of the National Academy of Sciences · 1990 · 691 citations

Amyloid Fibril, Alzheimer's Disease, Senile Systemic Amyloidosis +8