Concepedia

Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK–mTOR–SREBP signaling pathway

Hai Yan Quan, Do Yeon Kim, Soo Jung Kim, Hee Kyung Jo, Go Woon Kim, Sung Hyun Chung

Biochemical Pharmacology · 2013 · 151 citations · 25 references

DOI

Concepts

References

25

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

, , +16

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

, , +17

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Li Yu, Shanqin Xu, Maria M. Mihaylova et al. · Cell Metabolism · 2011 · 1.7K citations · Full text

, , +17

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

Thomas Porstmann, Cláudio R. Santos, B Griffiths et al. · Cell Metabolism · 2008 · 1.4K citations · Full text

, , +16

Preparation of rat liver cells

Per O. Seglen · Experimental Cell Research · 1973 · 1.1K citations

, , +9