Differential Roles of PKC-θ in the Regulation of Intracellular Calcium Concentration in Primary T Cells

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Zuoming Sun, Chris Arendt, Wilfried Ellmeier et al. · Nature · 2000 · 894 citations

Life Sciences, Immunology, Molecular Biology +14

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

Yuri Sykulev, Michael Joo, Irina Vturina et al. · Immunity · 1996 · 706 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Transcriptional Mechanisms Underlying Lymphocyte Tolerance

Fernando Macián, Francisco Garcı́a-Cózar, Sin‐Hyeog Im et al. · Cell · 2002 · 674 citations · Full text

Life Sciences, Cell Biology, Immunology +12

T cell killing does not require the formation of a stable mature immunological synapse

Marco A. Purbhoo, Darrell J. Irvine, Johannes B. Huppa et al. · Nature Immunology · 2004 · 578 citations

Life Sciences, Cell Biology, Immunology +12