Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors

Therapeutic Targeting of Transcription in Acute Promyelocytic Leukemia by Use of an Inhibitor of Histone Deacetylase

Raymond P. Warrell, Lizhong He, Victoria M. Richon et al. · JNCI Journal of the National Cancer Institute · 1998 · 513 citations · Full text

Medicine, Oncology, Pharmacology +17

Treatment of Episodic Hyperammonemia in Children with Inborn Errors of Urea Synthesis

Saul W. Brusilow, Mark M. Danney, Lewis Waber et al. · New England Journal of Medicine · 1984 · 234 citations

Medicine, Pediatrics, Pharmacotherapy +16

A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies.

Jeremy L. Gilbert, Sharyn D. Baker, M K Bowling et al. · PubMed · 2001 · 209 citations

Pharmacy, Oncology, Pharmacology +16

A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.

Michael A. Carducci, Jeremy L. Gilbert, M K Bowling et al. · PubMed · 2001 · 204 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Phenylacetylglutamine May Replace Urea as a Vehicle for Waste Nitrogen Excretion

Saul W. Brusilow · Pediatric Research · 1991 · 170 citations · Full text

Pharmacy, Biochemistry, Nutrition +9