Concepedia

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

Y Li, X Ye, Chalet Tan, J. Zha, Jinfeng Liu, Dara Kallop, Mary J. C. Ludlam, Lin Pei

Oncogene · 2009 · 284 citations · 46 references

DOI

Concepts

References

46

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

Peter C. Maisonpierre, Chitra Suri, Pamela F. Jones et al. · Science · 1997 · 3.6K citations

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TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response

Carla V. Rothlin, Sourav Ghosh, Elina I. Zúñiga et al. · Cell · 2007 · 1K citations · Full text

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Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

Daniel Dumont, Gérard Gradwohl, Gua-Hua Fong et al. · Genes & Development · 1994 · 983 citations · Full text

, , +14

Increased Vascularization in Mice Overexpressing Angiopoietin-1

Chitra Suri, Joyce McClain, Gavin Thurston et al. · Science · 1998 · 816 citations

, , +13

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

John P. O’Bryan, Roy A. Frye, Patricia C. Cogswell et al. · Molecular and Cellular Biology · 1991 · 723 citations · Full text

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