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Man-designed bleomycins: Significance of the binding sites as enzyme models and of the stereochemistry of the linker moiety

Enzyme ModelsMedicinal ChemistryBioorganic ChemistryAldo-keto ReductaseBiochemistryNatural SciencesRational Drug DesignLinker MoietySynthetic BiologyMolecular BiologyMan-designed BleomycinsChemical BiologyStructure-function Enzyme KineticsPharmaceutical ChemistryStructural Biology