Inhibition of RXR and PPARγ ameliorates diet-induced obesity and type 2 diabetes

Toshimasa Yamauchi, Hironori Waki, Junji Kamon, +22

Journal of Clinical Investigation

Mutagenic Principle(s) in Tryptophan and Phenylalanine Pyrolysis Products

Takashi Sügimura, Takashi Kawachi, Minako Nagao, +9

Proceedings of the Japan Academy

BiotechnologyMutagenic PrincipleBiochemistryPyrolysis Process

Potent estrogen agonists based on carborane as a hydrophobic skeletal structure

Yasuyuki Endo, Toru Iijima, Yuko Yamakoshi, +5

Chemistry & Biology

Medicinal ChemistryBiochemistryMedicineNatural SciencesHormonal Receptor +6

Stereochemistry of N-methylbenzanilide and benzanilide

Akiko Itai, Yoshiharu Toriumi, Nobuo Tomioka, +3

Tetrahedron Letters

HeterocyclicOrganic ChemistryStereoselective SynthesisChemistryHeterocycle Chemistry

Automatic creation of drug candidate structures based on receptor structure. Starting point for artificial lead generation.

Yoshihiko Nishibata, Akiko Itai

Tetrahedron

Pharmaceutical ResearchDrug TargetEngineeringHit IdentificationDrug Design +13

Host-guest complex formation between a water-soluble polyparacyclophane and a hydrophobic guest molecule

Kazunori Odashima, Akiko Itai, Yöichi Iitaka, +1

Journal of the American Chemical Society

Organic Charge-transfer CompoundMolecular SciencesEngineeringWater-soluble PolyparacyclophaneChemical Analysis +13

Aromatic architecture. Use of the N-methylamide structure as a molecular splint

Kentaro Yamaguchi, Go Matsumura, Hiroyuki Kagechika, +4

Journal of the American Chemical Society

Aromatic ArchitectureEngineeringChemical AnalysisBiochemistryNatural Sciences +12

Inhibition of IκB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury

Yasuyuki Onai, Jun Suzuki, T KAKUTA, +6

Cardiovascular Research

Preference for cis-amide structure in N-acyl-N-methylanilines

Akiko Itai, Yoshiharu Toriumi, Shoichi Saito, +2

Journal of the American Chemical Society

Molecular SciencesChemical AnalysisCis-amide StructureAltmetric Attention ScoreChemometrics +7

Isolation and structure studies of mutagenic principles in amino acid pyrolysates.

Takuo Kosuge, Kuniro Tsuji, Keiji Wakabayashi, +9

Chemical and Pharmaceutical Bulletin

Amino AcidsBasic FractionsStructure StudiesMolecular BiologyChemical Biology +14